Violent metaphors

My latest for Forbes discusses the new paper by Rascovan and colleagues, “Emergence and Spread of Basal Lineages of Yersinia pestis during the Neolithic Decline.”

Researchers investigated the hypothesis that the so-called “Neolithic Decline”—population decreases throughout Europe—was caused at least in part by pandemics. To do this, they cleverly made use of one feature of paleogenomics that often causes researchers to tear their hair out. When we sequence or genotype ancient DNA extractions, we get back data from all the DNA extracted from the ancient source, including large amounts of microbial DNA. This can be incredibly frustrating if you’re trying to reconstruct a genome of the human whose bone (or tooth, or hair) you’re extracting from; it can be enormously expensive to sequence enough DNA to get a whole human genome. However, in this case, the researchers were able to look at published datasets to see…

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